Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:38 PM
Ignite Modification Date:
2025-12-24 @ 11:38 PM
NCT ID:
NCT00178451
Eligibility Criteria:
Inclusion Criteria:
Subjects will be eligible if the following criteria are met:
* Ability to provide written informed consent and comply with study assessments for the full duration of the study.
* Age \>18 years
* Diagnosis of \>75% asymptomatic carotid artery stenosis by ultrasound or angiographic evaluation
* No contraindication to Abciximab or anticoagulation
* Ability to insonate an adequate window for Transcranial Doppler Imaging pre-operatively
* In women of childbearing capacity a negative pregnancy test
* Signed authorization of release of protected health care information
Exclusion Criteria:
* Inability to insonate an ipsilateral window; bilateral monitoring will be performed when possible.
* CT or MRI positive CVA within past 12 weeks
* Active internal bleeding
* Recent within six weeks gastrointestinal or genitourinary bleeding of clinical significance
* Bleeding diathesis
* Administration of oral anti-coagulants within seven days unless prothrombin time is less than or equal to 1.2 times control
* History of CVA within two years or CVA with a significant residual neurological deficit
* Thrombocytopenia (\<100,000 cells/uL)
* Recent (within six weeks) major surgery or trauma Intracranial neoplasm, AVM, or aneurysm
* Severe uncontrolled hypertension
* Presumed or documented history of vasculitis
* Use of intravenous dextran before PCI or intent to use during an intervention
* Known hypersensitivity to any component of ReoPro
* Known hypersensitivity to murine proteins
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00178451
Study Brief:
Protocol Section:
NCT00178451