Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:38 PM
Ignite Modification Date:
2025-12-24 @ 11:38 PM
NCT ID:
NCT07019051
Eligibility Criteria:
Inclusion Criteria:
* Age ≥18 years
* Admission to the intensive care unit (ICU)
* Clinical indication for initiation of continuous veno-venous hemodiafiltration (CVVHDF)
* Ability to obtain adequate transthoracic echocardiographic (TTE) images prior to CVVHDF
* Written informed consent obtained from the patient's legal representative
Exclusion Criteria:
* Acute coronary syndrome, severe valvular disease, or pericardial effusion affecting cardiac function
* Cardiac arrhythmias such as atrial fibrillation or ventricular tachycardia that interfere with accurate Doppler measurements
* Presence of cardiac devices such as pacemakers, LVADs, or implantable cardioverter defibrillators (ICDs)
* Poor echocardiographic window due to severe lung disease or chest wall abnormalities
* Estimated life expectancy \<24 hours or do-not-resuscitate (DNR) orders in place
* Inability to obtain informed consent due to lack of legal representative
* Transfer to another facility before CVVHDF initiation or change in renal replacement strategy (e.g., switch to peritoneal dialysis)
* Incomplete echocardiographic measurement due to technical limitations
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07019051
Study Brief:
Protocol Section:
NCT07019051