Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:37 PM
Ignite Modification Date:
2025-12-24 @ 11:37 PM
NCT ID:
NCT00522756
Eligibility Criteria:
Inclusion criteria:
* age greater than or equal to 18 years
* elective or urgent CABG +/- valve surgery, or elective or urgent isolated valve surgery
* exposure to cardiopulmonary bypass
* stable kidney disease: less than 25% change in serum creatinine during 3 months before surgery
* Estimated glomerular filtration rate, by Modification of Diet in Renal Disease (MDRD) equation, less than or equal to 60 ml/min/1.73m2
Exclusion criteria:
* emergency CABG, cardiac transplantation, or insertion of VAD
* planned off-pump surgery
* N-acetylcysteine given in last 72 hours prior to operation
* radiocontrast given in last 48 hours prior to operation
* acute renal failure (greater than 25% increase in serum creatinine from preadmission baseline)
* glomerular filtration rate less than 15 ml/min or chronic dialysis
* prior renal transplantation
* enrollment in another research study, with the exception of MUHC study SDR-05-033
* LV ejection fraction less than or equal to 20%
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00522756
Study Brief:
Protocol Section:
NCT00522756