Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:37 PM
Ignite Modification Date:
2025-12-24 @ 11:37 PM
NCT ID:
NCT00694356
Eligibility Criteria:
Inclusion Criteria:
* Has histologically- or cytologically-confirmed metastatic or locally advanced solid tumor(s) that has (have) failed to respond to standard therapy, or for which adequate standard therapy does not exist
* Has tumor(s) associated with insulin-like growth factor 1 receptor (IGF-1R) expression in the literature (e.g. prostate, pancreatic, colon, lung and breast)
* Has Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1
* Demonstrates adequate organ function
Exclusion Criteria:
* Has had chemotherapy, radiotherapy, or biological therapy within 4 weeks (6 weeks for nitrosoureas or mitomycin C) prior to registration
* Is concurrently using growth hormone (GH), or growth hormone inhibitor
* Has any active central nervous system (CNS) metastases and/or carcinomatous meningitis
* Has any primary CNS tumor - any symptomatic ascites or plural effusion
* Has a history or current evidence of any clinically significant disease that might confound the results of the study, complicate the interpretation of the study results, interfere with the participant's participation, or pose an additional risk to the participant
* Is pregnant or breast-feeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Study:
NCT00694356
Study Brief:
Protocol Section:
NCT00694356