Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:36 PM
Ignite Modification Date:
2025-12-24 @ 11:36 PM
NCT ID:
NCT05357456
Eligibility Criteria:
Inclusion Criteria:
* age 20-65 years;
* ≥ 6 years of education；
* right-handed;
* complete entire cognitive function tests;
* adrenal lesions ≥ 1 cm in diameter;
* patients with non-functioning adrenal adenomas;
* patients with autonomous cortisol secretion.
Exclusion Criteria:
* \< 6 years of education;
* age \< 20 years or \> 65 years;
* maximum diameter of AI \<1cm;
* active malignancies;
* with a history of thyroid disease;
* with a history of acute infection in the last month;
* central nervous system diseases, including brain trauma, intracranial hemorrhage, acute cerebral infarction, etc;
* contraindications of MRI examination: such as implantation of metal prosthesis in vivo, claustrophobia, etc;
* adrenal tuberculosis;
* suspected or diagnosed adrenocortical carcinoma;
* unable to complete entire cognitive function tests;
* current use of steroids or any drugs known to alter steroid synthesis or metabolism in the previous 3 months;
* clinical Cushing syndrome;
* Cushing disease;
* primary hyperaldosteronism;
* pheochromocytoma;
* severe impairment of heart, liver, kidney and other organs;
* pregnant and lactating women
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
65 Years
Study:
NCT05357456
Study Brief:
Protocol Section:
NCT05357456