Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:35 PM
Ignite Modification Date:
2025-12-24 @ 11:35 PM
NCT ID:
NCT00171756
Eligibility Criteria:
Inclusion Criteria:
* Male or female, aged between 18 - 75 years of age inclusively.
* Mild to moderate hypertension (MSDBP \>= 95 and \>= 110 mmHg and / or MSSBP \>140mm Hg) at visit 1, requiring pharmacological intervention. For newly diagnosed patients, hypertensive blood pressure values must be noted on at least two successive examinations prior to entry into the study. In addition, patients must require therapy despite having been following dietary \& lifestyle advice for at least 3 months.
* Written informed consent to participate in the study, prior to any study procedures.
* Ability to communicate and comply with all study requirements
Exclusion Criteria:
* o Uncontrolled hypertension defined as seated blood pressure of either systolic BP \>180 mmHg and/or diastolic BP \>110mmHg.
* Clinically significant laboratory abnormalities that may interfere with the assessment of safety and/or efficacy of the study drug
* Patients with severe medical condition(s) that in the view of the investigator may prohibit participation in the study
* Renal artery stenosis
* Diabetes Mellitus
* Any condition resulting from or leading to platelet or clotting abnormalities (eg. hemophilia, von Willebrand's disease).
* History of a vascular event or intervention (e.g. MI, PTCA or CABG) within 6 months preceding the study.
* History of clinically significant angina, LVH, transient ischemic attack, stroke, intermittent claudication, deep vein thrombosis (DVT), pulmonary embolism or peripheral vascular disease.
* Uncontrolled atrial fibrillation (\>100 b.p.m. at rest) or other conditions which may require anti-aggregant or anti-vitamin K therapies.
* Clinical evidence of congestive heart failure.
* Evidence of second or third degree heart block or sick sinus syndrome.
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT00171756
Study Brief:
Protocol Section:
NCT00171756