Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 4:00 PM
Ignite Modification Date:
2025-12-26 @ 4:00 PM
NCT ID:
NCT04528706
Eligibility Criteria:
Inclusion Criteria:
* Males aged ≥2 and ≤12 years with a diagnosis of X-linked ALD
* White matter involvement as determined by cerebral MRI lesions without Gd enhancement at baseline (Population 1), or with Gd enhancement at baseline (Population 2).
* Major Functional Disabilities (MFD) score of 0.
* Baseline Loes score \>0 and ≤10
* Gadolinium Intensity Score \>2
Exclusion Criteria:
* Previous HSCT
* Too far progressed inflammatory brain lesions
Healthy Volunteers:
False
Sex:
MALE
Minimum Age:
2 Years
Maximum Age:
12 Years
Study:
NCT04528706
Study Brief:
Protocol Section:
NCT04528706