Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 1:19 PM
Ignite Modification Date:
2025-12-26 @ 1:19 PM
NCT ID:
NCT06968806
Eligibility Criteria:
Inclusion Criteria:
* Patients with Stanford Type A aortic dissection confirmed by imaging and scheduled for emergency surgery.
Aged between 18 and 65 years.
Signed informed consent.
Exclusion Criteria:
* Patients who are unable to eat independently or require prolonged fasting.
History of malignant tumors.
Body weight \<50 kg.
Traumatic aortic dissection.
Patients with Marfan syndrome.
Unstable vital signs requiring preoperative mechanical support or resuscitation (e.g., IABP \[Intra-Aortic Balloon Pump\], ECMO \[Extracorporeal Membrane Oxygenation\], LVAD \[Left Ventricular Assist Device\])
Patients requiring preoperative endotracheal intubation.
Consciousness impairment, central nervous system dysfunction, or evidence of cerebral malperfusion syndrome upon admission.
Preoperative hematemesis, melena, fresh blood in stool, or symptoms of bowel dilation.
Clear evidence of limb malperfusion before surgery.
Presence of organ malperfusion syndrome.
Patients requiring interventional procedures to relieve organ malperfusion before surgery.
History of gastrointestinal ulcers or chronic gastrointestinal inflammatory diseases.
History of dialysis or renal insufficiency before admission.
History of liver disease.
Allergy to ketorolac tromethamine, aspirin, or other nonsteroidal anti-inflammatory drugs (NSAIDs).
Chronic inflammatory diseases, autoimmune diseases, or long-term use of steroids or NSAIDs for other reasons.
Absence of cerebral perfusion during deep hypothermic circulatory arrest.
History of major surgery or acute myocardial infarction within 90 days.
History of cardiac or major vascular surgery.
Pregnant or lactating women.
Patients who refuse to participate in this clinical trial or decline to sign the informed consent form.
Any other conditions deemed unsuitable for participation by the investigator.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT06968806
Study Brief:
Protocol Section:
NCT06968806