Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 1:18 PM
Ignite Modification Date:
2025-12-26 @ 1:18 PM
NCT ID:
NCT04351906
Eligibility Criteria:
Inclusion Criteria:
* mild-to-moderate ARDS according to the Berlin definition
* lung-protective ventilation with positive end-expiratory pressure (PEEP) \> 5 cm of water on mechanical ventilation expected to last \> 24 h
* hypercapnia \<80 mmHg
* bilateral opacities on chest imaging
Exclusion Criteria:
* age \< 18 years
* pregnancy
* patients with decompensated heart failure or acute coronary syndrome
* respiratory acidosis with persistent partial pressure of blood carbon dioxide (PCO2) levels \>80 mmHg
* acute brain injury
* severe liver insufficiency (Child-Pugh scores \> 7) or fulminant hepatic failure
* decision to limit therapeutic interventions
* catheter access to femoral vein or jugular vein impossible
* pneumothorax
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04351906
Study Brief:
Protocol Section:
NCT04351906