Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:33 PM
Ignite Modification Date:
2025-12-24 @ 11:33 PM
NCT ID:
NCT00169156
Eligibility Criteria:
Inclusion Criteria:
* Patients with histologically proven T-cell angioimmunoblastic lymphoma (AIL) on lymph node biopsy.
* Aged from 60 to 80 years.
* Patient not previously treated (except corticosteroids providing they have been initiated less than 10 days before inclusion).
* ECOG performance status 0 to 2.
* With a minimum of life expectancy \> 3 months.
* Negative HIV, HBV and HCV serological tests \< 4 weeks (except after vaccination).
* Having previously signed a written informed consent.
Exclusion Criteria:
* Any other histological type of T-cell lymphoma.
* Central nervous system or meningeal involvement by lymphoma.
* Contra-indication to any drug included in the R-CHOP regimen.
* Concurrent severe disease (according to the investigator's decision).
* Active bacterial, viral or fungal infection.
* Poor renal function (serum creatinine level \> 150 µmol/L) or impaired liver function tests (total bilirubin level \> 30 µmol/L, transaminases \> 2.5 upper normal limits) unless they are related to the lymphoma.
* Poor bone marrow reserve as defined by neutrophils \< 1.5 x 109/L or platelets \< 100 x 109/L, unless related to bone marrow infiltration.
* Any history of cancer during the last 5 years, with the exception of non basal cell carcinoma of the skin or in situ carcinoma of the cervix.
* Treatment with any investigational drug within 30 days before planned first cycle of chemotherapy and during the study.
* Patient under tutelage.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT00169156
Study Brief:
Protocol Section:
NCT00169156