Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:32 PM
Ignite Modification Date:
2025-12-24 @ 11:32 PM
NCT ID:
NCT04221256
Eligibility Criteria:
Neurological Healthy Participants Inclusion criteria
1. Men and women aged 18 years and older.
2. Ability to give informed consent.
Exclusion criteria
1. Contraindications to TMS: epilepsy or other seizure history, ferromagnetic metallic implants in the head, or pacemaker
2. Current or history of neurological disorders or brain lesions such as stroke, multiple sclerosis, tumor, traumatic brain injury, spinal cord injury
3. Diagnosis of major depressive disorder or other psychiatric disorder
4. Currently taking escitalopram or another selective serotonin reuptake inhibitor
5. Currently taking or have taken in the past month other medications or supplements that have known interactions with escitalopram or can precipitate serotonin syndrome when taken in combination with escitalopram: monoamine oxidase inhibitors, methylene blue, linezolid, serotonin norepinephrine reuptake inhibitors (SNRI), triptans, tricyclic antidepressants (TCAs), fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, St. John's wort
6. Known hypersensitivity to escitalopram or any of its inactive ingredients.
7. History of cerebral hemorrhage, gastrointestinal bleeding, or genitourinary bleeding.
8. History of prolonged QTc
9. Pregnant or breastfeeding
10. Social and/or personal circumstances that interfere with the ability to return for all study visits.
Stroke Patients Inclusion criteria
1. Men and women aged 18 years and older.
2. Ability to give informed consent.
3. History of ischemic stroke
Exclusion criteria
1. Contraindications to TMS: epilepsy or other seizure history, ferromagnetic metallic implants in the head, or pacemaker
2. Current or history of neurological disorders or brain lesions such as multiple sclerosis, tumor, traumatic brain injury, spinal cord injury
3. Diagnosis of major depressive disorder or other psychiatric disorder
4. Currently taking escitalopram or another selective serotonin reuptake inhibitor
5. Currently taking or have taken in the past month other medications or supplements that have known interactions with escitalopram or can precipitate serotonin syndrome when taken in combination with escitalopram: monoamine oxidase inhibitors, methylene blue, linezolid, serotonin norepinephrine reuptake inhibitors (SNRI), triptans, tricyclic antidepressants (TCAs), fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, St. John's wort
6. Known hypersensitivity to escitalopram or any of its inactive ingredients.
7. History of cerebral hemorrhage, gastrointestinal bleeding, or genitourinary bleeding.
8. History of prolonged QTc
9. Pregnant or breastfeeding
10. Social and/or personal circumstances that interfere with the ability to return for all study visits.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04221256
Study Brief:
Protocol Section:
NCT04221256