Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 12:14 PM
Ignite Modification Date:
2025-12-26 @ 12:14 PM
NCT ID:
NCT04518800
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 18 years, ≤70 years;
* Patients with Advanced Pancreatic Cancer diagnosed by histopathology，the expected survival time is more than 3 months;
* Neutropenia of ≥2 degree occurred with the nab-paclitaxel + S-1 regimen in the previous cycle.
* KPS score≥70;
* The peripheral blood routine of the patients was normal: ANC ≥ 2.0x10\^9/L, platelet count ≥ 90x10\^9/L, HB ≥ 80g/L before enrollment, and there was no bleeding tendency;
* Patients volunteered to participate in the trial, signed a written informed consent, willing to be followed up.
Exclusion Criteria:
* There are uncontrollable infections at the moment or systemic antibiotic treatment within 72 h of chemotherapy；
* Any abnormal bone marrow hyperplasia and other abnormal hematopoietic function；
* Patients who had received bone marrow or hematopoietic stem cell transplantation within 3 months；
* Patients with other malignancies that have not been cured or with brain metastases；
* Total bilirubin(TBIL), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) \>2.5 ULN, or \>5 ULN if there is liver metastasis;
* Serum creatinine (Cr) exceeded the upper limit of normal value；
* Allergic to this product or other biological products derived from genetically engineered escherichia coli；
* Suffering from a mental or nervous system disorder, without self-awareness or coordination；
* Patients expected to have a short survival or have difficulty tolerating chemotherapy；
* Pregnant or lactating female patients；
* Patients using other drugs of the same category or in clinical trials of other drugs；
* Not suitable for participation at investigators' discretion.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT04518800
Study Brief:
Protocol Section:
NCT04518800