Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:30 PM
Ignite Modification Date:
2025-12-24 @ 11:30 PM
NCT ID:
NCT01353456
Eligibility Criteria:
Inclusion Criteria:
* ASA I to III
* Age 18 to 80 years
* Scheduled for elective open and laparoscopic colonic or upper rectal resection in Queen Mary Hospital in Hong Kong
Exclusion Criteria:
* Extended resection involving other organs such as liver and urinary bladder
* Known drug allergy to alpha-2 agonists, opioids, non-steroidal anti-inflammatory drugs (NSAIDs) including COX-2 inhibitors or sulphonamides
* Regular use of clonidine, methyldopa, opioids or psychiatric drugs
* Alcohol or drug abuse
* Known history of second or third degree heart block, ischaemic heart disease, valvular heart disease, or heart failure
* Known history of pulmonary embolism or deep vein thrombosis
* Known history of sleep apnoea syndrome
* Impaired renal function, defined as preoperative serum creatinine level over 120µmol/L
* Impaired hepatic function, defined as preoperative serum albumin level less than 30g/L
* Impaired or retarded mental state
* Not self-ambulatory before operation
* Difficulties in using patient-controlled analgesia
* BMI \> 35kg/m2
* Pregnancy
* Patient refusal
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01353456
Study Brief:
Protocol Section:
NCT01353456