Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 11:11 AM
Ignite Modification Date:
2025-12-26 @ 11:11 AM
NCT ID:
NCT04981028
Eligibility Criteria:
Inclusion Criteria:
1.Acute episode TTP:
* Adult male or female patient ≥18 years of age at the time of signing the consent form, with a confirmed diagnosis of TTP (initial or relapse) based on ADAMTS13 \<10% 2. Known diagnosis of TTP:
* Adult male or female patient ≥ 18 years of age at time of signing the consent form, with a historical confirmed diagnosis of TTP (based on ADAMTS13 at initial presentation \<10%) 3. Healthy control:
* Non-blood relative / friend / carer of patients under the care of Haematology clinics at the Royal Liverpool University hospital or other participating centres.
Exclusion Criteria:
1. Acute episode of TTP:
* Participants less than 18 years old at the time of signing the consent form
* Patient with ADAMTS13 greater than 10%
* Patient with cancer or transplant associated MAHA will not be included
* Patient (or NOK, where patient does not have capacity) not wishing to consent to trial
2. Known diagnosis of TTP:
* Participants less than 18 years old at the time of signing the consent form
* Patient with ADAMTS13 greater than 10%
* Patient with cancer or transplant associated MAHA will not be included
* Patient (or NOK, where patient does not have capacity) not wishing to consent to trial
3. For healthy control:
* Participants less than 18 years old at the time of signing the consent form
* Participant not wishing to consent to trial
* Any personal or family history of thrombotic microangiopathy
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04981028
Study Brief:
Protocol Section:
NCT04981028