Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 11:09 AM
Ignite Modification Date:
2025-12-26 @ 11:09 AM
NCT ID:
NCT03137212
Eligibility Criteria:
Inclusion Criteria:
* Aged 19 to 70 years old, gender not limited
* 30 minutes or more persistent ischemia chest pain, and symptoms can't ease by treated by nitroglycerin
* In two or more lead ecg ST-segment（the line between QRS complex finish point and the start point of T wave in electrocardiogram) elevation ≥ 0.1mv, or two or more than two neighboring chest lead ST-elevation ≥0.2mv
* Persistent ischemia chest pain less than 6 hours, door to balloon time\>90 minutes and transfer time \>120 minutes
* Accept coronary arteriography and intervention treatment
* Signed informed consent
Exclusion Criteria:
* Pregnancy and lactation, menstrual period women
* Blood disease, clotting hemorrhagic disease, any part of active bleeding or bleeding tendency physique
* History of trauma in two months, including biopsy and received surgical operation
* History of the great vessels punctured in two weeks that could not oppression
* History of ischemic or hemorrhagic stroke and cerebrovascular accident
* Cardiac shock,reinfarction again, right ventricular myocardial infarction, history of cardiopulmonary resuscitation (CPR)
* History of PCI or coronary artery bypass grafting（CABG）
* Killip classification level III（a standard of heart function classification） or above, or cardiac mechanical complications such as cardiac rupture
* History of eyeground hemorrhage
* Currently use of therapeutic doses of anticoagulants, such as warfarin, etc
* Uncontrolled hypertension, systolic blood pressure before thrombolysis is still 160 mmHg or higher, diastolic blood pressure is still 100 mmHg or higher
* Active internal bleeding (such as gastrointestinal bleeding), urogenital system, or have not cure of peptic ulcer in four weeks
* Severe liver and kidney dysfunction
* Intracranial tumor, suspicious aortic dissection, arteriovenous malformation, aneurysm
* Thrombolysis treatment in one week
* Allergies of thrombolysis drug or contrast
* Participated in any clinical trials within three months
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
19 Years
Maximum Age:
70 Years
Study:
NCT03137212
Study Brief:
Protocol Section:
NCT03137212