Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 11:07 AM
Ignite Modification Date:
2025-12-26 @ 11:07 AM
NCT ID:
NCT01241812
Eligibility Criteria:
Inclusion Criteria:
* age greater than 50 years (to meet the American College of Rheumatology clinical definition of OA)
* radiographically confirmed knee OA in the medial compartment of the tibiofemoral joint
* knee pain during walking greater than 3/10 (based on an 11-point scale; 0 = "no pain", 10 = "maximal pain") on most days of the previous month
* predominance of pain/tenderness over the medial (inside) region of the knee
Exclusion Criteria:
* articular cartilage degradation in the lateral tibiofemoral compartment greater than the medial (medial compartment OA is more common than lateral and the KAM is a validated measure of medial compartment loading only)
* currently in a structured exercise program
* medical condition precluding exercise
* inflammatory arthritic condition
* history of knee replacement surgery
* recent use of corticosteroids (oral or via injection)
* unable to attend exercise training sessions at UBC
* pain originating predominantly from the patellofemoral joint
* inability to ambulate without a gait aid
* non-English speaking (questionnaires are in English and must be completed by the study participant only)
* recent (within 6 months) arthroscopic knee surgery
* significant hip or back pain (limits the ability to perform the testing and exercises)
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
85 Years
Study:
NCT01241812
Study Brief:
Protocol Section:
NCT01241812