Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:56 AM
Ignite Modification Date:
2025-12-26 @ 10:56 AM
NCT ID:
NCT03774108
Eligibility Criteria:
Inclusion Criteria:
* Both sexes,
* Age ≥18 years of age
* With a diagnosis of HIV-1 infection,
* That they are receiving TARE for at least 12 months (time necessary to establish a stable reservoir),
* Patients with undetectable viral load (\<40 copies / mL) for at least 12 months,
* Have a CD4 + level\> 200 cells / μL,
* That they do not have a diagnosis of co-infection with HCV or HBV,
* Patients who do not have a severe alcohol intake (\<21 glasses / week in men and \<14 glasses / week in women),
* Patients who do not use drugs during the last 90 days prior to the screening visit, or during the study,
* Who wish to participate voluntarily in the study and give their written consent.
Exclusion Criteria:
* Individuals with a known hypersensitivity / allergy to metformin.
* Patients with contraindications to the use of metformin \*.
* Individuals who are actively involved in an experimental therapy study or who have received experimental therapy in the last 6 months.
* People suffering from stage IV-V chronic kidney disease, uncontrolled heart failure or active infections.
* Individuals with diabetes mellitus (according to the criteria of the American Diabetes Association \*).
* Patients with indication for the use of statins, aspirin or immunomodulators.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03774108
Study Brief:
Protocol Section:
NCT03774108