Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:28 PM
Ignite Modification Date:
2025-12-24 @ 11:28 PM
NCT ID:
NCT02013856
Eligibility Criteria:
Inclusion Criteria:
* Men and women ≥ 50 years of age
* Systolic blood pressure 130 - 159 mmHg
Exclusion Criteria:
* History of cardiovascular events such as stroke, myocardial infarction trans- ischaemic attacks or peripheral vascular disease
* Kidney or liver disease/problems
* Diabetes
* Asthmatics (unless no medication taken for 1 year - occasional use will be assessed on an individual basis)
* Prescribed anti-hypertensive medication
* HRT (unless the participant has used the therapy for ≥ 6 months)
* Lipid lowering therapies e.g. statins
* Other medications that may affect any of the study outcome measures e.g. vasodilators (this will be assessed on a case by case basis)
* Current smoker (or stopped for less than 3 months)
* Throat surgery or neck injury
* Allergy to apples
* Consumption of fish oil supplements unless willing to discontinue them up for 4 weeks preceding the start of the study and for the duration of the study. (All other supplements will be assessed on a case by case basis)
* Gastro-intestinal diseases (excluding hiatus hernia unless symptomatic or study intervention/procedure is contra-indicated).
* Parallel participation in another research project which involves dietary intervention
* Participation in another research project which has involved blood sampling within the last four months unless the total amount of combined blood from both studies does not exceed 470 ml.
* Has donated or intends to donate blood within 16 weeks prior to or during the study period.
* Depressed or elevated blood pressure measurements (\<90/50 or 95/55 if symptomatic or \>160/100 (mmHg)) during the course of the trial.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Study:
NCT02013856
Study Brief:
Protocol Section:
NCT02013856