Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-26 @ 10:36 AM
Ignite Modification Date:
2025-12-26 @ 10:36 AM
NCT ID:
NCT06288828
Eligibility Criteria:
Inclusion Criteria:
* The diagnosis of cirrhosis is confirmed either through liver biopsy ,and/or compatible features on ultrasonography/ computer tomography or magnetic resonance imaging.
* The age range is between 45 and 75 years.
* Participants are classified as Child Pugh score class A.
* Participants report a physical inactivity, defined as engaging in physical activity for less than 150 minutes of moderate-intensity physical activity per week, or less than 75 minutes of vigorous-intensity physical activity per week, or an equivalent combination of both.
Exclusion Criteria:
* Active hepatocellular carcinoma (HCC) or remission of HCC within the past 3 months.
* Untreated large esophageal varices (EV) greater than F2 or history of upper gastrointestinal bleeding from portal hypertension or gastric varices.
* Active or history of hepatic encephalopathy (HE).
* Inpatient hospitalization for any reason or discharge from the hospital within the past 3 months.
* Complete portal vein thrombosis.
* Transjugular intrahepatic portosystemic shunt.
* Contraindications to exercise, such as recent myocardial infarction, unstable angina, electrocardiography changes within the past 24 hours, complete heart block, acute congestive heart failure, uncontrolled hypertension, hemoglobin level less than 11 g/dL, platelet count less than 50,000 cells/mm 3 .
* End-stage renal disease without dialysis.
* Severe orthopedic problems that limit the ability to exercise.
* Inability to communicate with the research team via telemedicine system.
* Body mass index (BMI) exceeding 35 kg/m 2 .
* On alpha or beta-blocker
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
45 Years
Maximum Age:
75 Years
Study:
NCT06288828
Study Brief:
Protocol Section:
NCT06288828