Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:19 PM
Ignite Modification Date:
2025-12-24 @ 11:19 PM
NCT ID:
NCT03121456
Eligibility Criteria:
Inclusion Criteria:
* Patient with Diffuse Large B-Cell Lymphoma confirmed histologically
* Patient with a tumor mass defined as measurable according to the RECIST 1.1 criteria,
* Patient requiring a standard first-line chemotherapy treatment (Rituximab -Cyclophosphamide - Hydroxyadriamycin - Oncovin - Prednisone = R-CHOP every 21 days),
* Patient older than 18 years,
* Performance status less than or equal to 2,
* Biological assessment meeting the following criteria: creatinine \<150 μmol / l or creatinine clearance\> 40 ml / min, total bilirubin \<30 μmol / l, transaminases \<2.5 x ULN
* Patient of childbearing age must agree to use Means of effective contraception during the treatment period,
* Patient having read the information note and having signed informed consent,
* Patient with Health care insurance available.
Exclusion Criteria:
* History of malignant hemopathy or solid tumor
* History of previous chemotherapy
* Contraindication to one of the examinations studied (Claustrophobia, Pacemaker ...)
* Patient included in another clinical trial for which a period of exclusion is mentioned.
* Patient considered to be a vulnerable person; Vulnerable persons are defined in article L1121-5 to - 8: Pregnant women, women who are pregnant, women who are breastfeeding, Persons deprived of their liberty by a judicial or administrative decision, persons who are hospitalized without consent under Articles L. 3212-1 and L. 3213-1 which do not fall under the provisions of Article L. 1121-8 and persons admitted to a health or social institution for purposes other than research Persons who are the subject of a legal protection measure or are unable to give their consent.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
19 Years
Study:
NCT03121456
Study Brief:
Protocol Section:
NCT03121456