Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:18 PM
Ignite Modification Date:
2025-12-24 @ 11:18 PM
NCT ID:
NCT07105956
Eligibility Criteria:
Inclusion Criteria:
* Volunteer for the trial, with the patient or their legal guardian signing the informed consent form.
* Volunteers are not limited by gender, and the age range is from 18 to 75 years old, including both ends.
* The patient is diagnosed with Alzheimer's disease (AD), supported by a positive amyloid PET scan.
* The patient has completed Tau PET scan.
Exclusion Criteria:
* Individuals with a history of allergy to drugs chemically or biologically similar to TSPO, a history of atopy, or currently suffering from allergic diseases.
* Use of anti-inflammatory drugs, including corticosteroids and immunosuppressants, within the past 14 days, which may interfere with the accuracy of inflammation imaging.
* Presence of other coexisting neurological diseases, such as stroke, Parkinson's disease, brain tumors, or mental disorders, including depressive disorder and schizophrenia.
* Severe cardiac, pulmonary, hepatic, or renal dysfunction, or uncontrolled systemic diseases; 5. Presence of metal implants contraindicated for MRI, including but not limited to cardiac pacemakers, artificial heart valves, and metal stents.
* Claustrophobia or inability to tolerate prolonged examinations.
* Pregnant women (defined as those with a positive urine pregnancy test) or breastfeeding women.
* Patients whose physical condition is unsuitable for radioactive tracer-based imaging examinations.
* Other circumstances deemed unsuitable for participation in the trial by the researcher.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT07105956
Study Brief:
Protocol Section:
NCT07105956