Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:16 PM
Ignite Modification Date:
2025-12-24 @ 11:16 PM
NCT ID:
NCT07003256
Eligibility Criteria:
Inclusion Criteria:
* After undergoing Mediterranean gene testing, reviewing the history of blood transfusions, and conducting a blood routine examination, the patient was diagnosed with severe thalassemia.
* Children aged 2 - 17 years old.
* Agree to the haploidentical transplantation, and the team has evaluated that there are no transplantation contraindications.
Exclusion Criteria:
* There is a fully matched donor, and transplantation with a half - matched donor is not agreed.
* For donors and recipients, the transaminase is more than twice the normal value.
* Donor specific antibody Greater than 5000, and after antibody treatment, it should not be lower than 3000.
* Positive for hepatitis B DNA.
* There is an active infection.
* After evaluation by the transplantation team, there are contraindications for transplantation.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
2 Years
Maximum Age:
17 Years
Study:
NCT07003256
Study Brief:
Protocol Section:
NCT07003256