Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:10 PM
Ignite Modification Date:
2025-12-24 @ 11:10 PM
NCT ID:
NCT07082569
Eligibility Criteria:
Inclusion Criteria
* Adult patients (≥18 years old)
* Receiving positive-pressure mechanical ventilation
* Under light or no sedation (e.g., RASS score between -2 and 0)
* Clinically assessed by the treating physician as not yet ready for weaning from mechanical ventilation
* Hemodynamically stable at the time of measurement
* Presence of an arterial catheter in place for blood gas analysis
* Written informed consent obtained from the patient's legal representative Exclusion Criteria
* Acute or chronic neurological disease affecting brainstem function or pupillary responses
* Dyssynchrony with the ventilator or need for high ventilatory support adjustments
* Facial injuries, edema, or conditions precluding accurate pupillometry
* Use of neuromuscular blocking agents within the prior 6 hours
* Severe metabolic or acid-base imbalances that may influence autonomic regulation
* Concurrent participation in another interventional study that could affect neurological or autonomic outcomes
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07082569
Study Brief:
Protocol Section:
NCT07082569