Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:10 PM
Ignite Modification Date:
2025-12-24 @ 11:10 PM
NCT ID:
NCT03923569
Eligibility Criteria:
Inclusion Criteria:
For all participants:
* age from 50 to 90 years old
* affiliated to the French health care system
For AD patients:
* meeting International Working Group (IWG)-2 criteria for diagnosis
* Mini-Mental State Examination (MMSE) ≥18 (Greco version)
For healthy volunteers:
* MMSE\>25
* Dubois 5 words test ≥ 9
Exclusion Criteria:
For all participants:
* Pregnancy
* people not able to give consent
* contraindication for MRI (metallic body parts, claustrophobia),
* aphasia, apraxia or agnosia
* neurological (other than AD) or any other serious disease (cancer, addiction, systemic disease)
* non treated sleep apnea
* major depression or anxiety for more than 3 months (Beck\>10) or psychiatric disease
* documented epilepsy
* use of neuroleptics (more than one dose per day)
* use of antiepileptics
* use of benzodiazepines at a dose superior or equal to two intakes per day
* use of antidepressants
* restless leg syndrome treated by dopaminergic agonists.
For AD patients:
* other causes of dementia
* non-degenerative neurological lesions
* white matter hypersignals
* acute cognitive deficits
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
50 Years
Maximum Age:
90 Years
Study:
NCT03923569
Study Brief:
Protocol Section:
NCT03923569