Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:10 PM
Ignite Modification Date:
2025-12-24 @ 11:10 PM
NCT ID:
NCT03813069
Eligibility Criteria:
Laboratory trial eligibility criteria
1. Participant is aged \> 18 years and \< 65 years and in good health
2. Participant has a good understanding of the procedures of the study and agrees to abide to these procedures
3. Participant is able to communicate well with the investigator, and attend the laboratory for all aspects of the laboratory studies
4. Participant has no known adverse reactions, or evidence at screening of adverse reactions, to the commercially available repellents DEET, PMD, IR3535, Picaridin or Permethrin, or to Vanilla
5. Participant has no known history of skin allergies or hypersensitivity to topical creams
6. Participant agrees to a pre-trial skin reactivity test for all the repellents that will be used in the trial
7. If in the event of the participant experiencing an adverse reaction to a repellent during the trial, the participant agrees to inform his/her general practitioner and seek appropriate treatment if necessary
8. Participant is willing to allow laboratory-reared Musca sorbens flies to land and crawl on their arm, during the modified arm-in-cage assay, for periods of up to ten minutes at a time
9. Participant agrees not to use any perfumed or scented product, including bathing products, for a 24-hour period before each laboratory session
10. Participant has signed informed consent
11. Participant is not a smoker, and will agree to refraining from smoking for the 12 hours before each laboratory trial
Field trial eligibility criteria
1. Participant lives in the designated study site
2. Participating households must be within a one-hour drive of Feya General Hospital
3. Participant considers themselves to be in good health, as does the parent or guardian
4. Participant is aged \> 3 years and \< 12 years
5. Participant has a good understanding of the procedures of the study and agrees to abide to these procedures
6. The parent or guardian of the participant has a good understanding of the procedures of the study and agrees to abide to these procedures
7. Participant is able to communicate well with the investigator or fieldworker who is conducting the study
8. Participant has no known adverse reactions to the commercially available repellents DEET, PMD, IR3535, Picaridin or Permethrin, or to Vanilla
9. Participant has no known history of skin allergies or hypersensitivity to topical creams
10. Participant agrees to a pre-trial skin reactivity test for all the repellents that will be used in the trial
11. If in the event of the participant experiencing an adverse reaction to a repellent during the trial, the participant can request medical advice from the Stronger-SAFE field team nurses if they wish
12. Participant is willing to sit still on a chair outside their house, for sequential periods of up to ten minutes, allowing wild fly contact and landing on the body and face, as much as possible without disturbing fly behaviour
13. Participant agrees not to use any perfumed or scented product, including bathing products, for a 24-hour period before each laboratory session
14. Able and willing to give fully informed assent
15. The parent or guardian has signed informed consent
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
3 Years
Maximum Age:
65 Years
Study:
NCT03813069
Study Brief:
Protocol Section:
NCT03813069