Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:10 PM
Ignite Modification Date:
2025-12-24 @ 11:10 PM
NCT ID:
NCT04342169
Eligibility Criteria:
Inclusion Criteria:
* Patient age ≥18 years, competent to provide consent
* Within 48 hours of positive nucleic acid test for SARS-CoV-2
Exclusion Criteria:
* Patient already prescribed chloroquine or hydroxychloroquine
* Allergy to hydroxychloroquine
* History of bone marrow or solid organ transplant
* Known G6PD deficiency
* Chronic hemodialysis, peritoneal dialysis, continuous renal replacement therapy or Glomerular Filtration Rate \< 20ml/min/1.73m2
* Known liver disease (e.g. Child Pugh score ≥ B or AST\>2 times upper limit)
* Psoriasis
* Porphyria
* Known cardiac conduction delay (QTc \> 500mSec) or taking any prescription medications known to prolong QT interval
* Concomitant use of digitalis, flecainide, amiodarone, procainamide, or propafenone
* Seizure disorder
* Prisoner
* Weight \< 35kg
* Inability to follow-up - no cell phone or no address or not Spanish or English speaking
* Receipt of any experimental treatment for SARS-CoV-2 (off-label, compassionate use, or trial related) within the 30 days prior to the time of the screening evaluation
* Patient or another member of patient's household has been already enrolled in this study.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04342169
Study Brief:
Protocol Section:
NCT04342169