Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:09 PM
Ignite Modification Date:
2025-12-24 @ 11:09 PM
NCT ID:
NCT04616469
Eligibility Criteria:
Inclusion Criteria:
* Patients who are free from any physical or mental handicapping condition and no contributory systemic disease.
* Age between 30-60 years old.
* Males \& Females.
* Patients' acceptance for participating in the trial through an informed consent
* Maxillary permanent premolar teeth:
* Diagnosed clinically and radiographically with pulp necrosis
* With or without periapical radiolucency
* Negative response of pulp tissue to thermal and electric pulp tester
* Possessing two independent roots each having a type I canal
* Patent canals with no internal calcification or resorptive lesions
* Fully formed roots
* Root curvatures less than 30
Exclusion Criteria:
* Patient with contributory medical condition
* Badly destructed teeth
* Patients with pre-operative pain
* Patients having significant systemic disorders
* Patients with two or more adjacent teeth requiring root canal therapy
* Patients who had received antibiotics in the last month
* Teeth presenting with:
* Positive response to thermal or electric pulp tester
* History of trauma or previous endodontic treatment
* Immature or open apices
* Association with acute periapical abscess and swelling or fistulous tract
* Fused roots at any level
* Canals larger than size 15# K-file
* Periodontonal/ endodontic lesions
* Mobility higher than grade I
* Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.
* Severe root curvature (\>30)
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
30 Years
Maximum Age:
60 Years
Study:
NCT04616469
Study Brief:
Protocol Section:
NCT04616469