Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:33 PM
Ignite Modification Date:
2025-12-24 @ 1:33 PM
NCT ID:
NCT07235995
Eligibility Criteria:
Inclusion Criteria:
* Age ≥ 60 years;
* Admitted to ICU after a noncardiac surgical procedure
* Moderate to severe acute pain, with a postoperative pain score ≥ 5 based on the 11-point Numerical Pain Rating Scale (NPRS)
* Signed informed consent form
Exclusion Criteria:
* Preoperative medical history: schizophrenia, epilepsy, Parkinson's disease, or severe myasthenia gravis
* History of psychiatric disease or significant neurocognitive disorder such as dementia or retardation, making POD assessment impossible
* Language or communication barrier making POD assessment impossible
* Intracranial surgery
* Severe hepatic dysfunction prohibiting the use of acetaminophen per the standard of care
* Participation in a competing study within 30d
* Patients experienced intraoperative or postoperative complications, and the investigator determined the subject was unsuitable to continue participation in the study
* Intolerant to paracetamol or opioid drugs
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
60 Years
Study:
NCT07235995
Study Brief:
Protocol Section:
NCT07235995