Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:08 PM
Ignite Modification Date:
2025-12-24 @ 11:08 PM
NCT ID:
NCT03840369
Eligibility Criteria:
Inclusion Criteria:
1. Adult participants represent a typically developing nervous system as a more reliable target for this stage of research.
2. The presence of a PTSD diagnosis made by a physician will ensure participants are experiencing significant symptomatology and may benefit from treatment.
3. The cutoff score on the PCL-5 will ensure that participants are experiencing similar levels of symptoms to each other.
4. Need to have tried at least two types of treatment in the past
Exclusion Criteria:
1. Significant past medical history including seizures, stroke, severe traumatic brain injury, or central nervous system cancers may interfere with our evaluation of treatment outcome and will be criteria for exclusion.
2. Metal in head/neck/eye is a contraindication to safety in the MRI scanner and TMS protocol.
3. Women who are pregnant will not be included in the study due to potential risk of seizure during TMS. To determine if a patient is pregnant we will ask when their last menstrual cycle occurred. If there is a possibility of pregnancy, we will ask the participant to follow-up with their family doctor to confirm. We will then ask the participant to provide a written note from their treating practitioner stating they are not pregnant.
4. Active suicidality
5. Wellbutrin or benzodiazepine intake of more than 200mg/day, or more than 15 mg of Zopiclone per day as these medications lower seizure threshold
6. Trauma experienced less than a year ago and/or trauma experienced only as a child
7. Drug and/or alcohol abuse within the last 3 months (diagnosed by Canadian guidelines)
8. Diagnosed schizophrenia, untreated bipolar disorder, or psychosis
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT03840369
Study Brief:
Protocol Section:
NCT03840369