Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:33 PM
Ignite Modification Date:
2025-12-24 @ 1:33 PM
NCT ID:
NCT03651895
Eligibility Criteria:
Inclusion Criteria:
* Age between 40 and 75 years
* Clinical diagnosis of COPD confirmed with spirometry (Post-bronchodilator FEV1/FVC \<70%).
* Smoking history \>15 pack years
* Absence of infection \>8 weeks prior to study entry
* No use of antibiotics and/or oral corticosteroids \>8 weeks prior to study entry
* Able to understand and consent to the study procedures
Exclusion criteria:
* Diabetes including diabetes diagnosed at screening
* History of hepatic or renal impairment or diagnosed on screening bloods
* Patients already taking metformin irrespective of indication
* Known allergy or hypersensitivity to metformin
* Pregnancy or breastfeeding
* Any other significant medical condition likely to interfere with the study
* Unable to provide informed consent
* Excessive alcohol intake (\>21 units/week)
* BMI \< 18.5kg/m2
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
75 Years
Study:
NCT03651895
Study Brief:
Protocol Section:
NCT03651895