Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:05 PM
Ignite Modification Date:
2025-12-24 @ 11:05 PM
NCT ID:
NCT04726969
Eligibility Criteria:
Inclusion Criteria:
* Aged between 12 and 60 years
* Written informed consent signed by either parents/caregivers for underage adolescents (aged 12-17 years) or by the participant him/herself (18-60 years of age); and written assent by underage participant
* Agree to comply with study procedures, including provision of two stool samples at the beginning (baseline) and at follow-up assessment 14-21 days after treatment
* Willing to be examined by a study physician prior to treatment
* At least two slides of the quadruple Kato-Katz thick smears positive for T. trichiura and infection intensities of at least 48 EPG
Exclusion Criteria:
* Presence or signs of major systemic illnesses, e.g. body temperature ≥ 38°C, severe anemia (below 80g/l Hb according to WHO) upon initial clinical assessment
* Known or suspected infection with Loa loa
* History of acute or severe chronic disease
* Abnormal liver function assessed by multiple biochemical blood-based analyses
* Recent use of anthelmintic drug (within past 4 weeks)
* Attending other clinical trials during the study
* Pregnancy, lactating, and/or planning to become pregnant within the next 3 months
* Known allergy to study medications (i.e. albendazole, ivermectin or moxidectin)
* Taking medication with known contraindication to or interaction with study drugs
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
12 Years
Maximum Age:
60 Years
Study:
NCT04726969
Study Brief:
Protocol Section:
NCT04726969