Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:04 PM
Ignite Modification Date:
2025-12-24 @ 11:04 PM
NCT ID:
NCT02064569
Eligibility Criteria:
Inclusion Criteria:
Documented diagnosis of LHON based on a genetic test confirming the presence of the G11778A mutation in the mitochondrial ND4
Age 18 years old or older at the time of study entry (informed consent signature)
Visual acuity ≤ 1/10 of the less functional eye
Exclusion Criteria:
Any known allergy or hypersensibility to one of the product used during the trial
Contraindication to IVT surgery (anaemia Hb \<8g/dl, severe cardiovascular disease, severe coagulopathy…)
Disorder of the ocular humors and of the internal retina involving visual disability
Glaucoma
Presence of other pathology whose symptoms or associated treatments might affect the retina or the optic nerve Vascular retinal occlusion
Narrow angle contra-indicating pupillary dilation
Other cause of optic neuropathy (inflammatory conditions or exposure to toxins...)
Patients presenting known mutation of other genes implicated in pathological retinal conditions
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02064569
Study Brief:
Protocol Section:
NCT02064569