Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 11:03 PM
Ignite Modification Date:
2025-12-24 @ 11:03 PM
NCT ID:
NCT00587769
Eligibility Criteria:
Inclusion Criteria:
* at least 18 years of age
* have smoked 10 or more cigarettes per day for at least 6 months
* are motivated to stop smoking.
Exclusion Criteria:
* an unstable medical condition
* unstable angina, myocardial infarction, or coronary angioplasty within the past 3 months or an untreated cardiac dysrhythmia
* personal history of seizures
* closed head trauma with any loss of consciousness or amnesia in the last 5 years
* ever history of closed head trauma with \> 30 minutes of loss of consciousness or amnesia or resulting in skull fracture or subdural hematoma/brain contusion
* a history or psychosis, bipolar disorder, bulimia or anorexia nervosa)
* have current depression as assessed by Center for Epidemiologic Studies Depression (CES-D)
* have active substance abuse other than nicotine
* have used an investigational drug within the last 30 days
* are currently using a behavioral or pharmacologic tobacco treatment and unwilling or unable to discontinue use
* use of bupropion or varenicline in the previous 3 months
* current (past 14 days) use of antipsychotic or antidepressant
* an allergy to bupropion or varenicline
* untreated hypertension or baseline systolic blood pressure \> 180 or diastolic \> 100
* have another member of their household already participating in this study.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00587769
Study Brief:
Protocol Section:
NCT00587769