Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:58 PM
Ignite Modification Date:
2025-12-24 @ 10:58 PM
NCT ID:
NCT04387669
Eligibility Criteria:
Inclusion Criteria:
* Moderate to severe ARDS as per the Berlin definition (Partial pressure of oxygen (PaO2)/Fraction of inspired oxygen (FiO2) \< 200 mmHg) and within 72h of onset, with a FiO2 \> 60%
* Receiving assist/control mechanical ventilation with continuous sedation and neuromuscular blocker
* In supine position during the procedures and measurements
* Patients \> 18 years of age
Exclusion Criteria:
* Patients \< 18 years of age
* Pregnant woman
* Patient deprived of freedom or under a legal protective measure
* Hemodynamic instability defined as a mean arterial pressure \< 65 mmHg or increasing doses of vasopressor drugs
* Pneumothorax, pneumomediastinum, pleural fistula, sub-cutaneous emphysema
* Chronic or recent severe cardiac dysfunction
* Patient with a PEEP \> 15 cmH20 before inclusion
* Patient with no therapeutic perspective; candidate for palliative care exclusively or with end of life decision before inclusion
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04387669
Study Brief:
Protocol Section:
NCT04387669