Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:58 PM
Ignite Modification Date:
2025-12-24 @ 10:58 PM
NCT ID:
NCT04902469
Eligibility Criteria:
Inclusion Criteria:
* Aged 18-49
* Right-handed
* Fluent in English
* Intact sense of smell
* Pass an MRI safety screening and along these lines will need to be 250lbs or less to safely enter the MRI
* No drug dependence outside of nicotine or caffeine
* Must fit into one of two categories of smokers, daily or nondaily, as confirmed by verbal self-report and a baseline CO reading; Daily smokers: must smoke 10-30 cigarettes per day for at least 12 months, Nondaily smokers: must smoke for 1-14 days of the last 30 days with no more than 20 cigarettes a day
* Need to have access to a working smartphone to complete the ecological momentary assessment portion of the study
Exclusion Criteria:
* Medical conditions that contraindicate nicotine use
* Not fluent in English
* Illiterate
* Current neurological or psychotic disorders
* Current psychoactive drug use
* MRI contraindications such as stroke history, pregnancy, metal in the body, history of aneurysms, or serious head injury
* Individuals will also be excluded if they report any allergies to the odors used in our study.
* Baseline CO readings will need to be consistent with our criteria for daily and nondaily smokers for participants to be considered eligible. Specifically, we plan to rule out extremely heavy smokers (nondeprived CO \> 55, for whom the smoking abstinence requirement may be too extreme to allow a sensitive test of our OC manipulation) and daily smokers with a nondeprived CO reading \<10 PPM as this would raise concerns that they do smoke enough to be classified as a daily smoker.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
49 Years
Study:
NCT04902469
Study Brief:
Protocol Section:
NCT04902469