Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:57 PM
Ignite Modification Date:
2025-12-24 @ 10:57 PM
NCT ID:
NCT06873269
Eligibility Criteria:
Inclusion Criteria:
* aged 18 year or older
* diagnosed with locally advanced HCC without extra-hepatic metastases
* HCC must not be amendable to treatment by surgical resection or percutaneous radiofrequency ablation
* after assessment by the investigator and multidisciplinary tumor board, the patient is considered suitable for protocol treatment with Holmium-166 TARE
* ECOG performance status 0-2
* child-Pugh A-B
* tumor response evaluable with mRECIST criteria during follow-up
Exclusion Criteria:
* prior treatment with any of the following treatment modalities for HCC: systemic therapy, hepatic radiation therapy
* currently enrolled in clinical studies where patient receive investigational therapeutic drug
* metastatic disease
* concurrent malignancy
* active contra-indications to angiography or selective catherization (i.e. severe vascular disease or bleeding diathesis)
* uncontrolled and/or severe comorbidities (active infection, heart failure,...) with limited estimated life expectancy
* history of or know allergic reactions to used compounds
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06873269
Study Brief:
Protocol Section:
NCT06873269