Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:56 PM
Ignite Modification Date:
2025-12-24 @ 10:56 PM
NCT ID:
NCT00668369
Eligibility Criteria:
Inclusion Criteria:
* Liver transplantation for HCV-related liver disease performed at least 3 years before weaning;
* Peripheral blood Vgd1+/Vgd2+ T cell ratio \>2.33 and/or increased expression of KLRF1 and SLAMF7 genes in peripheral blood (measured by qPCR).
* No indication for treatment with pegylated a-interferon plus ribavirin during the weaning procedure;
* Stability of liver function tests for at least 6 months;
* No evidences of autoimmune liver disease;
* Absence of acute and/or chronic rejection episodes during the 12 months before weaning;
* Basal liver biopsy without signs of acute and/or chronic rejection.
* Absence of decompensated chronic liver disease.
Exclusion Criteria:
* HIV infection
* Double liver-kidney transplantation
* HCV cholestatic fibrosing hepatitis
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT00668369
Study Brief:
Protocol Section:
NCT00668369