Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:53 PM
Ignite Modification Date:
2025-12-24 @ 10:53 PM
NCT ID:
NCT04655469
Eligibility Criteria:
Inclusion Criteria:
* Histologically confirmed diagnosis of head and neck squamous cell carcinoma (HNSCC)
* Head and Neck primary tumor site: oral cavity, oropharynx, larynx or hypopharynx
* Treated between 01-2008 and 12-2017
* Clinical stage III and IV (a, b) according to TNM 7th edition
* No distant metastases (M0)
* Treated with curative intent: primary definitive radiation therapy with or without systemic treatment
* Availability of baseline imaging:
* Planning CT scan of the HN region in treatment position, with RT-structures available, performed with contiguous cuts of 2-3 mm or less in slice thickness with i.v. contrast
* (if available) FDG-PET in treatment position
Exclusion Criteria:
* Any previous HNC
* Patients with previous malignancies in the last 5 years before treatment for HNC, with the exception of surgically cured carcinoma in situ of the cervix, in situ breast cancer, incidental finding of stage T1a or T1b prostate cancer, and basal/squamous cell carcinoma of the skin
* Any previous malignancy that was treated with surgery and/or radiation of the head and neck region
* Histological type other than HNSCC
* Cancers originating in the oral cavity, nasopharynx, salivary glands or sinonasal area
* Postoperative radiation treatment setting
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04655469
Study Brief:
Protocol Section:
NCT04655469