Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:48 PM
Ignite Modification Date:
2025-12-24 @ 10:48 PM
NCT ID:
NCT04977869
Eligibility Criteria:
Inclusion Criteria:
* 1\) Age ≥ 18 years, male or female
* 2\) Diagnosis of acute ischemic stroke within 24 hours of symptom onset and underwent endovascular thrombectomy (EVT) adhering to current guidelines for large vessel occlusion in the anterior circulation (confirmed by computed tomography angiography or digital subtraction angiography)
* 3\) Pre-EVT NIHSS ≥ 6
* 4\) Premorbid mRS ≤ 2
* 5\) Written informed consent obtained from the patient or legally responsible person
Exclusion Criteria:
* 1\) Contraindication of endovascular thrombectomy
* 2\) Contraindication of remote ischemic conditioning, such as severe soft tissue injury, fracture, or vascular injury in the upper limb, acute or subacute venous thrombosis, arterial occlusive disease, and subclavian steal syndrome
* 3\) Head CT showing cerebral hernia and midline displacement
* 4\) Pregnancy or lactation
* 5\) Previous remote ischemic conditioning therapy or similar treatment
* 6\) Severe hepatic and renal dysfunction
* 7\) Life expectancy of less than 3 months or inability to complete the study for other reasons
* 8\) Unwilling to be followed up or poor compliance
* 9\) Current or past participation in other clinical research, or participation in this study within 3 months prior to admission
* 10\) Other conditions that the researchers think make the patient unsuitable for the study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04977869
Study Brief:
Protocol Section:
NCT04977869