Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:47 PM
Ignite Modification Date:
2025-12-24 @ 10:47 PM
NCT ID:
NCT04682769
Eligibility Criteria:
Inclusion Criteria:
* Patients seen at the Washington University Medical Center with coronary heart disease (CHD) documented by coronary angiography or history of acute coronary syndrome (ACS).
* On a stable medication regimen (only minor changes in drug or dosage in last 30 days) are eligible for recruitment.
* Meet the diagnostic criteria for a depressive disorder, score ≥ 14 on the Beck Depression Inventory (BDI-II), and not meet any exclusion criteria.
Exclusion Criteria:
* Thyroid disease or thyroid medications.
* Moderate to severe cognitive impairment.
* Major psychiatric comorbidities.
* Taking antidepressants other than a selective serotonin reuptake inhibitor (SSRI).
* Suicidal features.
* Current substance abuse.
* New York Heart Association (NYHA) class III or higher or a recent (\<3 months) acute coronary syndrome (ACS), coronary artery bypass graft surgery, cardiac hospitalization, or cardiac-related emergency department visit.
* Advanced malignancy, a disability that would prevent compliance with the study protocol, or physician or patient refusal.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04682769
Study Brief:
Protocol Section:
NCT04682769