Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 1:29 PM
Ignite Modification Date:
2025-12-24 @ 1:29 PM
NCT ID:
NCT00599495
Eligibility Criteria:
Inclusion Criteria:
* Multiple Myeloma stage II or III acc. to Salmon and Durie (chemosensitive or refractory) and relapse or progression after high dose chemotherapy with autologous stem cell support
* Age 18-60 years
* ECOG-performance status 0-1
* Availability of a HLA-compatible unrelated donor (HLA-A, -B, -DRB1, -DQB1)
Exclusion Criteria:
* Serious concomitant medical disease that would limit life span or ability to tolerate chemotherapy
* Severe cardiac failure (ejection fraction \< 40%)
* Severe impairment of renal function (Creatinine clearance \< 50ml/min)
* Severe impairment of liver function (bilirubine \> 2 fold of upper limits of normal)
* Pregnant or lactating women
* Other major organ or system dysfunctions(GI, neurological, psychiatric dysfunctions that would impair tolerance of chemotherapy or prolonged haematological recovery)
* Positivity for HIV
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT00599495
Study Brief:
Protocol Section:
NCT00599495