Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:45 PM
Ignite Modification Date:
2025-12-24 @ 10:45 PM
NCT ID:
NCT02135835
Eligibility Criteria:
Inclusion Criteria:
* Clinical diagnosis of Acute Heart Failure according to Guidelines for the diagnosis and treatment of acute heart failure 2010 of Chinese Medical Association(Participants whose Heart function grade of NYHA is Ⅲ～Ⅳ).
* LVEF≤40%.
* NT-pro-BNP ≥1400 pg/mL or BNP ≥ 350pg/mL.
* Ages 18-80, male or female.
* All participants signed the informed consent.
Exclusion Criteria:
* Participants with abnormal liver function (ALT, AST≥3 times of upper limit of normal) or abnormal kidney function( Cr≥1.5 times of upper limit of normal or Cr \>3.0 mg/dl (\> 265 µmol/L)).
* SBP ≥ 150mmHg.
* Participants with severe chronic asthmatic bronchitis or acute episode of lung diseases.
* Participants with acute coronary syndrome, cardiogenic shock, aortic dissection, pulmonary embolism, severe ventricular arrhythmias, complete atrioventricular block without cardiac pacemaker, hypertrophic obstructive cardiomyopathy, restrictive cardiomyopathy and severe valvular disease without surgery.
* Participants with advanced cancer.
* Breastfeeding, pregnant and potentially fertile women participant.
* Participants with insanity.
* Known allergies with Shenfu Zhusheye or its ingredients in the past.
* Participants who have taken part in other clinical trials in last month.
* Participants who abuse alcohol or other drugs in last year.
* Participants who are not suitable for clinical trial under doctors' consideration.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT02135835
Study Brief:
Protocol Section:
NCT02135835