Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:40 PM
Ignite Modification Date:
2025-12-24 @ 10:40 PM
NCT ID:
NCT04759235
Eligibility Criteria:
Inclusion Criteria:
* Pathologically confirmed esophageal squamous cell carcinoma；
* AJCC 7th edition staging T3-T4a or N+；
* No radiotherapy or chemotherapy in the past；
* 18-75 years old；
* Hematology, biochemical and organ function indicators meet the following requirements: 1) White blood cells ≥ 3.0 x109/ L; 2)neutrophil cells ≥ 1.5 x109/ L; 3) Platelet count ≥85 x109/L; 4) Hemoglobin ≥90 g/L; 5) Total bilirubin ≤1.5 times normal value; 6) ALT≤ 1.5 x normal value; AST ≤1.5 times the normal value; 7) Serum creatinine ≤1.5 times the normal value, and creatinine clearance rate (Ccr) ≥60ml/min (Cockcroft-Gault);
* ECOG score 0-1 points;
* Able to eat a semi-liquid diet；
* sign an informed consent.
Exclusion Criteria:
* Have received radiotherapy or systemic chemotherapy;
* During pregnancy or lactation;
* Uncontrollable serious medical diseases;
* Unable to sign informed consent;
* With distant metastasis;
* Suffering from the second type of malignant tumor (except skin squamous cell carcinoma and carcinoma in situ of other organs) within the past 5 years；
* Those who cannot receive MRI examination;
* Chemotherapy drugs or contrast agents Allergic.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT04759235
Study Brief:
Protocol Section:
NCT04759235