Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:40 PM
Ignite Modification Date:
2025-12-24 @ 10:40 PM
NCT ID:
NCT02116335
Eligibility Criteria:
Inclusion Criteria:
* Men and premenopausal women (Ages 18-50 years old)
* Self-reported Black and White adults
* Lean adults (BMl \<25 kg/m\^)
* Obese adults (BMl \> 30 kg/m\^)
Exclusion Criteria:
* Having a BMI less than 16 kg/m2 (severely and very severely underweight) or that is greater than 40 kg/m2 (Class III obesity)
* Having evidence of cardiovascular, pulmonary, renal, hepatic, cerebral, or metabolic disease
* Having evidence of pregnancy
* Using medications that affect vascular tone (i.e., nitrates, etc.)
* Postmenopausal women
* Uncontrolled hypertension
* Individuals who are on a restricted salt diet
* Having a history of chronic pain
* Having a history of rheumatoid arthritis
* Using medications that are contraindicated with bosentan (i.e. glyburide, cyclosporine)
* Liver dysfunction (which may be identified with the blood sample we take)
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
50 Years
Study:
NCT02116335
Study Brief:
Protocol Section:
NCT02116335