Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:35 PM
Ignite Modification Date:
2025-12-24 @ 10:35 PM
NCT ID:
NCT03923335
Eligibility Criteria:
Inclusion Criteria:
1. TNM stage I-II (T1-4N0M0) colorectal cancer cases
2. receive radical surgical resection
3. have completed data of tumor location, histological type, behavioral characteristics or TNM staging
4. have tumor specimens and either a valid microsatellite instability (MSI) or immuno-histochemistry (IHC) data
5. have valid V-raf murine sarcoma viral oncogene homolog B1 (BRAF), kirsten rat sarcoma viral oncogene (KRAS), CpG island methylator phenotype (CIMP) results
6. have at least 4 years of follow-up
7. have valid time to local recurrence/metastasis in follow-up
8. have clinical/treatment record data and valid preoperative status of intestinal obstruction or perforation (IOP), counts of lymph node removed in surgical resection.
Exclusion Criteria:
1. have had a previous diagnosis of any cancer or presence of any tumor other than the CRC
2. have had inflammatory bowel disease
3. have had hereditary colorectal cancer syndromes, including Familial adenomatous polyposis, mutyh (MYH)-associated polyposis, Peutz-Jeghers syndrome, Juvenile polyposis coli, phosphate and tension homology deleted on chromosome ten (PTEN) tumor-hamartoma syndromes, Lynch Syndrome, and Familial Colorectal Cancer Type X.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
70 Years
Study:
NCT03923335
Study Brief:
Protocol Section:
NCT03923335