Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:33 PM
Ignite Modification Date:
2025-12-24 @ 10:33 PM
NCT ID:
NCT06804135
Eligibility Criteria:
Inclusion Criteria:
* Common Inclusion Criteria:
1. Age 18 years and above.
2. Ability to tolerate full course of pelvic radiotherapy+/- chemotherapy +/- brachytherapy.
3. Ability to understand and willingness to sign an informed consent document.
4. Should be willing to undergo extra biopsies and blood samples collection for translational research study.
Cohort A:
1. Patients diagnosed with LACC Stage IB2 - IIIC1, as per FIGO 2018 Classification for Radical Cohort.
2. Stage IIIB-IVA where palliative RT is indicated for palliative cohort.
3. No previous irradiation to the pelvis or chemo therapy.
Cohort B:
1. Patients diagnosed with LACC Stage IIIC2, as per FIGO 2018 Classification.
2. No previous irradiation to the pelvis or chemotherapy.
Cohort C:
1. Patients diagnosed with gynecological cancer and presenting with need of infield radiation.
2. Planned for reirradiation.
Exclusion Criteria:
1. Severe medical condition impairing complete treatment delivery.
2. Patients with immunocompromised states or active infection.
3. Patients on immunosuppressive drugs for other medical conditions.
4. Patients who will receive immune checkpoint inhibition (ICI) therapy.
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
18 Years
Study:
NCT06804135
Study Brief:
Protocol Section:
NCT06804135