Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:29 PM
Ignite Modification Date:
2025-12-24 @ 10:29 PM
NCT ID:
NCT01406535
Eligibility Criteria:
Inclusion Criteria:
* Stable angina pectoris
* Evidence for myocardial ischemia according to the presence of one or more of the followings:
* Typical angina during exercise test or
* Significant reversible perfusion defects on dipyridamole myocardial radionuclide study
* Coronary artery disease of at least one large epicardial coronary artery with ≥70% stenosis remaining from which new collaterals/vessels could be supplied
* Coronary artery disease judged to be unsuitable for surgical or percutaneous revascularisation ƒdue to extensive atherosclerosis
* Optimized anti-ischemic drug therapy (including beta-blocker therapy with at least 50% target dose)
Subject must be willing and able to give informed consent Eligible patients must fulfill all 6 inclusion criteria.
Exclusion Criteria:
* STEMI or NSTEMI within the past 3 months
* Revascularisation procedures within the last 3 months
* Severely reduced systolic left ventricular function EF \< 30%
* Systolic blood pressure \<120mmHg
* Chronic renal insufficiency with a serum creatinine \>2.5mg/dl
* Diabetes mellitus with proliferative retinopathy
* Diagnosed or suspected cancer
* Chronic inflammatory disease
* Therapy with nitrates and nicorandil
* Women who are pregnant or lactating
* Patients with a total occluded vessel and reversible perfusion defects at the marginal zone of scare tissue if they have no additional stenosed vessels causing significant reversible perfusion defects.
* Patients with a total occluded vessel and perfusion defect at rest despite evidence of vital myocardium, if they have no additional stenosed vessels causing significant reversible perfusion defects.
Eligible patients must demonstrate none of the exclusion criteria.
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT01406535
Study Brief:
Protocol Section:
NCT01406535