Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:21 PM
Ignite Modification Date:
2025-12-24 @ 10:21 PM
NCT ID:
NCT00776035
Eligibility Criteria:
Inclusion criteria
* Heart failure (HF) and a systolic ejection fraction \<45% per a recent echocardiogram report)
* Nonischemic HF New York Heart Association Class II-III
* Ambulatory
* Able to give informed consent
* On a stable medical regimen including the standard-of-care HF medications (i.e., a beta-blocker, ACE-inhibitor or angiotensin receptor blocker \[ARB\])
Exclusion criteria
* Participants who were pregnant or lactating
* Actively losing weight
* Nonsedentary (performing aerobic exercise \> 30 minutes x 3 times/week)
* Those who have more than Class I hypertension
* Those who require alterations in beta-blocker or ACE or ARB-inhibition medication
* Those with hypertrophic, constrictive, or restrictive cardiomyopathies
* Those unable to lie flat in the PET scanner
* Severe major organ system dysfunction (other than heart failure)
* Significant coronary artery disease by catheterization
* Those unable to give informed consent
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
20 Years
Maximum Age:
65 Years
Study:
NCT00776035
Study Brief:
Protocol Section:
NCT00776035