Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:16 PM
Ignite Modification Date:
2025-12-24 @ 10:16 PM
NCT ID:
NCT01852435
Eligibility Criteria:
Inclusion Criteria:
1. Histologically confirmed de novo diffuse large B-cell lymphoma or follicular lymphoma grade 3B
2. Age\>=16 y.o.,\<=80 y.o.
3. ECOG \< 3
4. No past history of malignancy
5. Radiologically measurable disease, CT imaging in screening showing 2 or more clearly demarcated lesions with a largest diameter \> 1.5 cm, or 1 clearly demarcated lesion with a largest diameter \> 2.0 cm.
6. Life expectancy\>6 months
7. Informed consented
Exclusion Criteria:
1. Chemotherapy before
2. Bone marrow transplantation before
3. History of malignancy
4. Active infectious disease requiring general antibiotics, anti-fungal or anti-virus therapy
5. Uncontrollable cardio-cerebral vascular, coagulative, autoimmune, serious infectious disease
6. Primary cutaneous, CNS, mediastinal DLBCL
7. LVEF≤50%
8. Other uncontrollable medical condition that may that may interfere the participation of the study
9. Lab at enrollment(unless caused by lymphoma)
* Neutrophile\<1.5\*10\^9/L
* Platelet\<80\*10\^9/L
* Hemoglobulin\<100g/L
* ALT or AST \>2\*ULN,AKP or bilirubin \>1.5\*ULN
* Creatinine\>1.5\*ULN
10. Not able to comply to the protocol for mental or other unknown reasons
11. Pregnant or lactation
12. Active liver or biliary disease
13. If HbsAg positive, should check HBV DNA, DNA positive patients cannot be enrolled. If HBsAg negative but HBcAb positive (whatever HBsAb status), should check HBV DNA,DNA positive patients cannot be enrolled.
14. HIV infection
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
16 Years
Maximum Age:
80 Years
Study:
NCT01852435
Study Brief:
Protocol Section:
NCT01852435