Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 10:15 PM
Ignite Modification Date:
2025-12-24 @ 10:15 PM
NCT ID:
NCT04850235
Eligibility Criteria:
Inclusion Criteria:
1. Patients with newly histologically confirmed non-keratinizing nasopharyngeal carcinoma, including WHO II or III.
2. Original clinical staged as III-IVa （according to the 8th AJCC edition).
3. No evidence of distant metastasis (M0).
4. Male and no pregnant female.
5. Satisfactory performance status: ECOG (Eastern Cooperative OncologyGroup) scale 0-1.
6. WBC ≥ 4×109 /L and PLT ≥100×109 /L and HGB ≥90 g/L.
7. With normal liver function test (ALT/AST ≤ 2.5×ULN, TBIL≤ 2.0×ULN).
8. With normal renal function test (Creatinine Clearance ≥ 60 ml/min ).
Exclusion Criteria:
1. Patients have evidence of relapse or distant metastasis.
2. Histologically confirmed keratinizing squamous cell carcinoma (WHO I).
3. Receiving radiotherapy or chemotherapy previously.
4. The presence of uncontrolled life-threatening illness.
5. Women of child-bearing potential who are pregnant or breastfeeding because of the potentially dangerous effects of the preparative chemotherapy on the fetus or infant.
6. Receiving other ways of anti-cancer therapy.
7. Suffered from other malignant tumors (except the cure of basal cell carcinoma or uterine cervical carcinoma in situ) previously.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT04850235
Study Brief:
Protocol Section:
NCT04850235